Strategies to control pertussis in infants

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Strategies to control pertussis in infants.

The UK is currently in the midst of a large outbreak of pertussis, with the highest morbidity and mortality occurring in young unimmunised infants. This review considers the potential strategies to optimise control of pertussis in infants, including vaccination of (1) adolescents, (2) close household contacts of newborn infants (cocooning), (3) newborn infants and (4) pregnant women. The paper ...

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Strategies to decrease pertussis transmission to infants.

The Global Pertussis Initiative (GPI) is an expert scientific forum addressing the worldwide burden of pertussis, which remains a serious health issue, especially in infants. This age cohort is at risk for developing pertussis by transmission from those in close proximity. Risk is increased in infants aged 0 to 6 weeks, as they are too young to be vaccinated. Older infants are at risk when thei...

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Transmission of Bordetella pertussis to young infants.

BACKGROUND Pertussis vaccination has reduced the number of notified cases in industrialized countries from peak years by more than 95%. The effect of recently recommended adult and adolescent vaccination strategies on infant pertussis depends, in part, on the proportion of infants infected by adults and adolescents. This proportion, however, remains unclear, because studies have not been able t...

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Protecting infants from pertussis.

QUESTION With the increased rate of pertussis in children, several families have asked me about ways to protect their young infants from pertussis infection. What should I recommend to these families? ANSWER Pertussis is a preventable disease that is endemic worldwide. In adults pertussis causes a mild coldlike illness followed by a persistent cough. In young infants it can cause apnea, seizu...

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Pertussis control: where to now?

ertussis is a disease of significant morbidity and, in infants, mortality. Regrettably, even though there is greater than 20-fold reduction in pertussis burden with immunisation,1 it persists globally as a significant public health problem. For more than two decades, Australia has had the highest reported rates of pertussis in the world.2 In the 1990s, this was driven by the introduction of man...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood

سال: 2013

ISSN: 0003-9888,1468-2044

DOI: 10.1136/archdischild-2012-302968